{"id":166,"date":"2025-06-18T02:35:04","date_gmt":"2025-06-17T18:35:04","guid":{"rendered":"http:\/\/www.leishidiet.com\/?p=166"},"modified":"2025-06-19T02:53:08","modified_gmt":"2025-06-18T18:53:08","slug":"%e5%b0%8f%e9%bc%a0%e8%83%86%e7%bb%93%e7%9f%b3%e6%a8%a1%e5%9e%8b%e7%9a%84%e8%87%b4%e7%9f%b3%e9%a5%b2%e6%96%99%e7%a0%94%e7%a9%b6","status":"publish","type":"post","link":"https:\/\/www.leishidiet.com\/?p=166","title":{"rendered":"\u5c0f\u9f20\u80c6\u7ed3\u77f3\u6a21\u578b\u7684\u81f4\u77f3\u9972\u6599\u7814\u7a76"},"content":{"rendered":"\n

\u7814\u7a76\u53d1\u73b0\uff0c\u80a0\u9053\u80c6\u56fa\u9187\u7684\u9ad8\u6548\u7387\u5438\u6536\u548c\u9ad8\u80c6\u56fa\u9187\u996e\u98df<\/a>\u65b9\u5f0f\uff08\u5982\u897f\u65b9\u996e\u98df<\/a>\u6a21\u5f0f\uff09\u662f\u5c0f\u9f20\u80c6\u7ed3\u77f3\u7684\u4e24\u4e2a\u91cd\u8981\u8d77\u56e0\u3002\u80a0\u9053\u5438\u6536\u80c6\u56fa\u9187\u540e\u8fd0\u9001\u81f4\u809d\u810f\u5e76\u5206\u6ccc\u4e8e\u80c6\u6c41\u7684\u8fd9\u4e00\u4ee3\u8c22\u901a\u8def\u4e00\u65e6\u53d7\u5230\u4e00\u4e9b\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u80c6\u56fa\u9187\u5c31\u5bb9\u6613\u51fa\u73b0\u7ed3\u6676\u5e76\u5bfc\u81f4\u80c6\u7ed3\u77f3\u7684\u5f62\u6210\uff0c\u5982\u80c6\u56fa\u9187\u7684\u8fc7\u91cf\u6444\u5165\u548c\u916f\u5316\u3001\u80a0\u7ec6\u80de\u5185\u8102\u8d28\u8f6c\u8fd0\u53d7\u635f\u3001\u4e73\u7cdc\u5fae\u7c92\u7684\u805a\u96c6\u7b49\u7b49\u56e0\u7d20\u3002\u80c6\u56fa\u9187\u7684\u8fc7\u91cf\u6444\u5165\u662f\u80c6\u7ed3\u77f3\u7684\u9996\u8981\u524d\u63d0\uff0c\u56e0\u6b64\uff0c\u901a\u8fc7\u996e\u98df\u6765\u8bf1\u5bfc\u5c0f\u9f20\u80c6\u56fa\u9187\u7ed3\u77f3\u662f\u826f\u597d\u7684\u9020\u6a21\u65b9\u6cd5\u4e4b\u4e00\u3002\u81f4\u77f3\u9972\u6599<\/a>\u7684\u4e3b\u4f53\u90e8\u5206\u548c\u5e38\u89c4\u9972\u6599\u57fa\u672c\u4e00\u81f4\uff0c\u9664\u4e86\u6ee1\u8db3\u5c0f\u9f20\u9700\u8981\u7684\u86cb\u767d\u8d28\u3001\u78b3\u6c34\u5316\u5408\u7269\u3001\u7ef4\u751f\u7d20\u3001\u77ff\u7269\u8d28\u7b49\u8425\u517b\u7269\u8d28\u4e4b\u5916\uff0c\u66f4\u91cd\u8981\u7684\u662f\uff0c\u81f4\u77f3\u9972\u6599\u8fd8\u9700\u989d\u5916\u8003\u8651\u8bbe\u8ba1\u4e0d\u540c\u7684\u9020\u6a21\u56e0\u5b50\u7ec4\u5408\u6765\u8bf1\u5bfc\u5c0f\u9f20\u80c6\u56fa\u9187\u7ed3\u77f3\u7684\u53d1\u751f\uff0c\u5982\u9ad8\u6bd4\u4f8b\u80c6\u56fa\u9187\u3001\u6cb9\u8102\u3001\u80c6\u9178\u7684\u4f7f\u7528\u7b49\u3002<\/p>\n\n\n\n

1964\u5e74\uff0cTepperman \u7b49\u7814\u7a76\u8005\u7387\u5148\u53d1\u73b0\u4e86\u5728\u5c0f\u9f20\u9972\u6599\u4e2d\u6dfb\u52a0\u80c6\u56fa\u9187\u548c\u80c6\u9178\u7684\u7ec4\u5408\u53ef\u4ee5\u6709\u6548\u5efa\u7acb\u5c0f\u9f20\u80c6\u7ed3\u77f3\u6a21\u578b<\/a>\u3002\u4ed6\u4eec\u7ed9\u5c0f\u9f20\u5582\u517b\u542b\u6709\u80c6\u56fa\u9187\u548c\u80c6\u9178\u7684\u81f4\u77f3\u9972\u6599\u540e\uff0c\u53d1\u73b0\u4ece\u80c6\u77f3\u4e2d\u63d0\u53d6\u51fa\u6765\u7684\u753e\u9187\u57fa\u672c\u4e0a\u662f\u80c6\u56fa\u9187\uff0c\u5360\u4e86\u7ed3\u77f3\u603b\u91cd\u91cf\u768494%\uff0c\u800c\u5355\u72ec\u5582\u517b1%\u80c6\u56fa\u91872~8\u4e2a\u6708\u5374\u4e0d\u80fd\u8bf1\u53d1\u51fa\u80c6\u7ed3\u77f3\uff0c\u4ee5\u6b64\u63a8\u6d4b\u80c6\u9178\u5728\u5c0f\u9f20\u80c6\u7ed3\u77f3\u6a21\u578b<\/a>\u5efa\u7acb\u4e2d\u5fc5\u4e0d\u53ef\u5c11\uff0c\u662f\u4fc3\u8fdb\u80c6\u77f3\u5f62\u6210\u7684\u91cd\u8981\u6761\u4ef6\u3002\u968f\u540e\uff0cHistochemica\u3001Matsumoto\u3001KR Wilund\u3001Shumeng Rena\u7b49\u7b49\u7814\u7a76\u8005\u5728\u81f4\u77f3\u9972\u6599\u4e2d\u8bbe\u8ba1\u9ad8\u8102\u80aa\u3001\u9ad8\u80c6\u56fa\u9187<\/a>\u3001\u548c\u4e00\u5b9a\u6bd4\u4f8b\u7684\u80c6\u9178\u8fdb\u884c\u8bf1\u5bfc\u5c0f\u9f20\u80c6\u56fa\u9187\u7ed3\u77f3\u7684\u53d1\u751f\uff0c\u7ed3\u679c\u5728\u8bf1\u5bfc8\u5468\u540e\u5c0f\u9f20\u90fd\u80fd\u4e0d\u540c\u7a0b\u5ea6\u6210\u6a21\u3002<\/p>\n\n\n\n

\u56e0\u6b64\uff0c\u6839\u636e\u4e0a\u8ff0\u7814\u7a76\u8005\u4ee5\u53ca\u5176\u4ed6\u7814\u7a76\u8005\u7684\u7ecf\u9a8c\uff0c\u5728\u76ee\u524d\u81f4\u77f3\u9972\u6599\u7684\u8bbe\u8ba1\u548c\u5e94\u7528\u4e2d\uff0c\u8102\u80aa\u7684\u7528\u91cf\u4e00\u822c\u4e3a15~30%\uff0c\u901a\u5e38\u4e3a\u732a\u6cb9\u6216\u8005\u9ec4\u6cb9\u7b49\u9ad8\u9971\u548c\u8102\u80aa\uff0c\u80c6\u56fa\u9187\u7684\u4f7f\u7528\u5242\u91cf\u4e3a1~1.25%\uff0c\u800c\u80c6\u9178\u7684\u7528\u91cf\u5219\u7a33\u5b9a\u57280.5%\uff08\u89c1\u88681\u6240\u793a\uff09\u3002<\/p>\n\n\n\n

\u8868<\/strong>1  \u4e0d\u540c\u9020\u6a21\u56e0\u5b50\u8bbe\u8ba1\u5bf9\u5c0f\u9f20\u80c6\u7ed3\u77f3\u9020\u6a21\u7684\u5f71\u54cd<\/p>\n\n\n\n

Table 1<\/strong> <\/strong> Effect of different factor on gallstone model of mice<\/p>\n\n\n\n

 <\/td>\u5c0f\u9f20\u54c1\u7cfbStrains<\/td>\u9020\u6a21\u56e0\u5b50\u8bbe\u8ba1factor design<\/td>\u9020\u6a21\u65f6\u95f4Time consuming<\/td>\u6210\u6a21\u7ed3\u679cStudy result<\/td><\/tr>
Tepperman, et al.<\/td>\u2013<\/td>\u732a\u6cb9(Lard)30.6%\uff1b\u80c6\u56fa\u9187(cholesterol) 1.0%<\/td>2~8\u5468(wk)<\/td>\u672a\u89c2\u5bdf\u5230\u6210\u77f3
No gallstones<\/td><\/tr>
Tepperman , et al.<\/td>\u2013<\/td>\u732a\u6cb9(Lard)30.6%\uff1b\u80c6\u56fa\u9187(Cholesterol) 1.0%\uff1b\u80c6\u9178(Cholic acid)0.5%<\/td>2~8\u5468(wk)<\/td>\u6210\u77f3
Gallstones observed<\/td><\/tr>
Alexander , et al.<\/td>C57BL6J<\/td>\u9ec4\u6cb9(Butter)19.4%\uff1b\u7389\u7c73\u6cb9(Corn oil)0.68%\uff1b\u80c6\u56fa\u9187(Cholesterol)0.38% \uff1b\u80c6\u9178(Cholic acid)0.5%<\/td>16\u5468(wk)<\/td>\u4e0d\u540c\u7a0b\u5ea6\u6210\u77f3
Different degrees of Gallstones <\/td><\/tr>
Matsumoto, et al.<\/td>C57BL6J<\/td>\u9ec4\u6cb9(Butter)19%\uff1b\u80c6\u56fa\u9187(Cholesterol)1.25%\uff1b\u80c6\u9178(Cholic acid)0.5%<\/td>4~8\u5468(wk)<\/td>4\u5468\u65f6\u65e0\u80c6\u7ed3\u77f3\uff0c8\u5468\u65f650%\u51fa\u73b0\u80c6\u7ed3\u77f3
No gallstones observed at fourth week ;50% gallstones observed at eighth week <\/td><\/tr>

KR Wilund, et al.<\/td>		C57BL6J<\/td>\u4e73\u810221%\uff1b\u80c6\u56fa\u9187(Cholesterol)1.25%\uff1b\u80c6\u9178(Cholic acid)0.5%<\/td>12\u5468(wk)<\/td>\u6210\u77f3
Gallstones observed<\/td><\/tr>
Sungsoon Fang, et al.<\/td>C57BL6J<\/td>\u65e0\u6c34\u4e73\u8102(Anhydrous milk fat)15%\uff1b\u7389\u7c73\u6cb9(Corn oil)2.0%\uff1b\u80c6\u56fa\u9187(Cholesterol)1.0%\uff1b\u80c6\u9178(Cholic acid)0.5%<\/td>8\u5468(wk)<\/td>\u6210\u77f3
Gallstones observed<\/td><\/tr>
\u6881\u9896\u7b49LiangY, et al.<\/td>C57BL6\/J<\/td>\u8102\u80aa15%\uff1b\u80c6\u56fa\u9187(Cholesterol)1.25%\uff1b\u80c6\u9178(Cholic acid)0.5%<\/td>8\u5468(wk)<\/td>\u6210\u77f3
Gallstones observed<\/td><\/tr>
Histochemica, et al.<\/td>C57BL<\/td>\u80c6\u56fa\u9187(Cholesterol)1%\uff1b\u80c6\u9178(Cholic acid)0.5%<\/td>8\u5468(wk)<\/td>\u672a\u89c2\u5bdf\u5230\u6210\u77f3\uff0c\u5904\u7406\u7ec4\u80c6\u6c41\u5bc6\u5ea6\u6700\u5927\u5e76\u5dee\u5f02\u663e\u8457
No gallstones, but The density of bile in treatment group was  highest and the difference was significant<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u663e\u793a\u8be6\u7ec6\u4fe1\u606f<\/p>\n\n\n\n

\u5c0f\u9f20\u80c6\u7ed3\u77f3\u6a21\u578b\u7684\u5efa\u7acb\u4e3a\u7814\u7a76\u540c\u6e90\u4eba\u7c7b\u7ed3\u77f3\u57fa\u56e0\u548c\u63a2\u7d22\u4eba\u7c7b\u80c6\u77f3\u5f62\u6210\u673a\u5236\u4ee5\u53ca\u5bf9\u75c7\u6cbb\u7597\u6253\u5f00\u4e86\u5927\u95e8\uff0c\u94fa\u5e73\u4e86\u9053\u8def\u3002\u81f4\u77f3\u9972\u6599\u7684\u7814\u5236\u4e0e\u5e94\u7528\uff0c\u4f5c\u4e3a\u80c6\u7ed3\u77f3\u7814\u7a76\u7684\u4e0a\u6e38\u5de5\u4f5c\uff0c\u663e\u5f97\u5c24\u4e3a\u91cd\u8981\u3002\u5408\u7406\u7684\u9020\u6a21\u56e0\u5b50\u8bbe\u8ba1\uff0c\u7a33\u5b9a\u7684\u5b89\u5168\u7684\u9972\u6599\u539f\u6599\u54c1\u8d28\uff0c\u5408\u9002\u7684\u5b9e\u9a8c\u52a8\u7269\u54c1\u7cfb\u9009\u62e9\uff0c\u662f\u80c6\u56fa\u9187\u7ed3\u77f3\u6a21\u578b\u6210\u529f\u5efa\u7acb\u7684\u6700\u91cd\u8981\u56e0\u7d20\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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